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2000年至2016年痛风在中国大陆的流行情况

Background:The prevalence of gout varied in different populations and it appeared to be increasing in the past decades.Gout is a serious health issue and is an independent risk factor for heart failure and metabolic. Therefore, we have used the method of meta-analysis to systematically evaluate the prevalence of gout in mainland China and have provided relevantly informative data for gout prevention and control.

 
Methods:Relevant articles from 2000 to 2016 October were identified by searching four electronic databases: PubMed,Chinese WanFang, CNKI, and Chongqing VIP. All of the calculations were performed using the MetaAnalyst beta 3.13 and R3.3 software.

 
Results:In all, 30 eligible articles (1 in English and 29 in Chinese) were included with a total sample size of 146,081.The pooled prevalence of gout was 1.1% (95% CI: 0.8%,1.5%). Subgroup analysis showed the following results: 1.7 and 0.5% for male and female; 1.3 and 1.0% for inland and coast, respectively; 1.4, 1.0 and 0.7% for urban, city and rural areas; 1.0 and 1.6% for community and hospital; 1.2, 1.7, and 0.8% for eastern, central and western region; 1.0, 1.1 and 1.3% for 2000–2005, 2006–2009 and 2010–2016,respectively.

 
Conclusion:The prevalence of gout in mainland China is an ascendant trend that differs according to sex and region.